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Flow virometry for process monitoring of live virus vaccines-lessons learned from ERVEBO

Direct at line monitoring of live virus particles in commercial manufacturing of vaccines is challenging due to their small size. Detection of malformed or damaged virions with reduced potency is rate-limited by release potency assays with long turnaround times. Thus, preempting batch failures cause...

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Detalles Bibliográficos
Autores principales:	Ricci, Geoffri, Minsker, Kevin, Kapish, Austin, Osborn, James, Ha, Sha, Davide, Joseph, Califano, Joseph P., Sehlin, Darrell, Rustandi, Richard R., Dick, Lawrence W., Vlasak, Josef, Culp, Timothy D., Baudy, Andreas, Bell, Edward, Mukherjee, Malini
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016999/ https://www.ncbi.nlm.nih.gov/pubmed/33795759 http://dx.doi.org/10.1038/s41598-021-86688-z

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