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Presence of complete murine viral genome sequences in patient-derived xenografts

Patient-derived xenografts are crucial for drug development but their use is challenged by issues such as murine viral infection. We evaluate the scope of viral infection and its impact on patient-derived xenografts by taking an unbiased data-driven approach to analyze unmapped RNA-Seq reads from 18...

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Detalles Bibliográficos
Autores principales:	Yuan, Zihao, Fan, Xuejun, Zhu, Jay-Jiguang, Fu, Tong-Ming, Wu, Jiaqian, Xu, Hua, Zhang, Ningyan, An, Zhiqiang, Zheng, W. Jim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017013/ https://www.ncbi.nlm.nih.gov/pubmed/33795676 http://dx.doi.org/10.1038/s41467-021-22200-5

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