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Region- and voxel-based quantification in human brain of [(18)F]LSN3316612, a radioligand for O-GlcNAcase

BACKGROUND: Previous studies found that the positron emission tomography (PET) radioligand [(18)F]LSN3316612 accurately quantified O-GlcNAcase in human brain using a two-tissue compartment model (2TCM). This study sought to assess kinetic model(s) as an alternative to 2TCM for quantifying [(18)F]LSN...

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Detalles Bibliográficos
Autores principales:	Lee, Jae-Hoon, Veronese, Mattia, Liow, Jeih-San, Morse, Cheryl L., Montero Santamaria, Jose A., Haskali, Mohammad B., Zoghbi, Sami S., Pike, Victor W., Innis, Robert B., Zanotti-Fregonara, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017047/ https://www.ncbi.nlm.nih.gov/pubmed/33796956 http://dx.doi.org/10.1186/s13550-021-00780-z

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