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In vivo N-Terminomics Highlights Novel Functions of ADAMTS2 and ADAMTS14 in Skin Collagen Matrix Building

A disintegrin and metalloproteinase with thrombospondin type I motif (ADAMTS)2 and ADAMTS14 were originally known for their ability to cleave the aminopropeptides of fibrillar collagens. Previous work using N-terminomic approach (N-TAILS) in vitro led to the identification of new substrates, includi...

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Detalles Bibliográficos
Autores principales: Leduc, Cédric, Dupont, Laura, Joannes, Loïc, Monseur, Christine, Baiwir, Dominique, Mazzucchelli, Gabriel, Deroanne, Christophe, Colige, Alain, Bekhouche, Mourad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017238/
https://www.ncbi.nlm.nih.gov/pubmed/33816558
http://dx.doi.org/10.3389/fmolb.2021.643178