CRISPR-cas9 Screening Identified Lethal Genes Enriched in Cell Cycle Pathway and of Prognosis Significance in Breast Cancer

BACKGROUND: Lethal genes have not been systematically analyzed in breast cancer which may have significant prognostic value. The current study aims to investigate vital genes related to cell viability by analyzing the CRISPR-cas9 screening data, which may provide novel therapeutic target for patient...

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Detalles Bibliográficos
Autores principales: Sun, Xi, Wang, Zheng, Chen, Xiaosong, Shen, Kunwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017240/
https://www.ncbi.nlm.nih.gov/pubmed/33816496
http://dx.doi.org/10.3389/fcell.2021.646774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017240/
https://www.ncbi.nlm.nih.gov/pubmed/33816496
http://dx.doi.org/10.3389/fcell.2021.646774

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