Cargando…

POLE and Mismatch Repair Status, Checkpoint Proteins and Tumor-Infiltrating Lymphocytes in Combination, and Tumor Differentiation: Identify Endometrial Cancers for Immunotherapy

OBJECTIVE: Although Polymerase-epsilon (POLE)-mutated and mismatch repair (MMR)-deficient endometrial cancers (ECs) are considered as promising candidates for anti-PD-1/PD-L1 therapy, selecting only these patients may exclude other patients who could potentially respond to this treatment strategy, h...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Dandan, Lei, Huajiang, Liu, Duanya, Bai, Hansong, Yang, Yue, Tang, Baijie, Li, Ke, Liu, Juan, Xu, Gang, Xiao, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017289/
https://www.ncbi.nlm.nih.gov/pubmed/33816285
http://dx.doi.org/10.3389/fonc.2021.640018