COVID-19 and Pembrolizumab-Induced Secondary Hemophagocytic Lymphohistiocytosis: a Case Report

Our case highlights SARS-CoV-2 and pembrolizumab as trigger of secondary hemophagocytic lymphohistiocytosis. Although it is a rare complication, it must be suspected in order to start specific treatment. In this context, intravenous immunoglobulins could be a therapeutic option.

Detalles Bibliográficos
Autores principales: Ramos-Ruperto, Luis, Busca-Arenzana, Carmen, Valdivieso, Juan, López-Granados, Eduardo, Robles-Marhuenda, Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Covid-19
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017431/
https://www.ncbi.nlm.nih.gov/pubmed/33824942
http://dx.doi.org/10.1007/s42399-021-00882-8
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author Ramos-Ruperto, Luis
Busca-Arenzana, Carmen
Valdivieso, Juan
López-Granados, Eduardo
Robles-Marhuenda, Ángel
author_facet Ramos-Ruperto, Luis
Busca-Arenzana, Carmen
Valdivieso, Juan
López-Granados, Eduardo
Robles-Marhuenda, Ángel
author_sort Ramos-Ruperto, Luis
collection PubMed
description Our case highlights SARS-CoV-2 and pembrolizumab as trigger of secondary hemophagocytic lymphohistiocytosis. Although it is a rare complication, it must be suspected in order to start specific treatment. In this context, intravenous immunoglobulins could be a therapeutic option.
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spelling pubmed-80174312021-04-02 COVID-19 and Pembrolizumab-Induced Secondary Hemophagocytic Lymphohistiocytosis: a Case Report Ramos-Ruperto, Luis Busca-Arenzana, Carmen Valdivieso, Juan López-Granados, Eduardo Robles-Marhuenda, Ángel SN Compr Clin Med Covid-19 Our case highlights SARS-CoV-2 and pembrolizumab as trigger of secondary hemophagocytic lymphohistiocytosis. Although it is a rare complication, it must be suspected in order to start specific treatment. In this context, intravenous immunoglobulins could be a therapeutic option. Springer International Publishing 2021-04-02 2021 /pmc/articles/PMC8017431/ /pubmed/33824942 http://dx.doi.org/10.1007/s42399-021-00882-8 Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Covid-19
Ramos-Ruperto, Luis
Busca-Arenzana, Carmen
Valdivieso, Juan
López-Granados, Eduardo
Robles-Marhuenda, Ángel
COVID-19 and Pembrolizumab-Induced Secondary Hemophagocytic Lymphohistiocytosis: a Case Report
title COVID-19 and Pembrolizumab-Induced Secondary Hemophagocytic Lymphohistiocytosis: a Case Report
title_full COVID-19 and Pembrolizumab-Induced Secondary Hemophagocytic Lymphohistiocytosis: a Case Report
title_fullStr COVID-19 and Pembrolizumab-Induced Secondary Hemophagocytic Lymphohistiocytosis: a Case Report
title_full_unstemmed COVID-19 and Pembrolizumab-Induced Secondary Hemophagocytic Lymphohistiocytosis: a Case Report
title_short COVID-19 and Pembrolizumab-Induced Secondary Hemophagocytic Lymphohistiocytosis: a Case Report
title_sort covid-19 and pembrolizumab-induced secondary hemophagocytic lymphohistiocytosis: a case report
topic Covid-19
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017431/
https://www.ncbi.nlm.nih.gov/pubmed/33824942
http://dx.doi.org/10.1007/s42399-021-00882-8
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