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An autism-associated calcium channel variant causes defects in neuronal polarity in the ALM neuron of C. elegans

Variants of the CACNA1C voltage-gated calcium channel gene have been associated with autism and other neurodevelopmental disorders including bipolar disorder, schizophrenia, and ADHD. The Timothy syndrome mutation is a rare de novo gain-of-function variant in CACNA1C that causes autism with high pen...

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Detalles Bibliográficos
Autores principales:	Buddell, Tyler, Quinn, Christopher C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Caltech Library 2021
Materias:	New Finding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017444/ https://www.ncbi.nlm.nih.gov/pubmed/33829152 http://dx.doi.org/10.17912/micropub.biology.000378

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