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Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma

The migrational propensity of neuroblastoma is affected by cell identity, but the mechanisms behind the divergence remain unknown. Using RNAi and time-lapse imaging, we show that ADRN-type NB cells exhibit RAC1- and kalirin-dependent nucleokinetic (NUC) migration that relies on several integral comp...

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Detalles Bibliográficos
Autores principales: Afanasyeva, Elena A, Gartlgruber, Moritz, Ryl, Tatsiana, Decaesteker, Bieke, Denecker, Geertrui, Mönke, Gregor, Toprak, Umut H, Florez, Andres, Torkov, Alica, Dreidax, Daniel, Herrmann, Carl, Okonechnikov, Konstantin, Ek, Sara, Sharma, Ashwini Kumar, Sagulenko, Vitaliya, Speleman, Frank, Henrich, Kai-Oliver, Westermann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017594/
https://www.ncbi.nlm.nih.gov/pubmed/33658318
http://dx.doi.org/10.26508/lsa.201900332

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