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Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma
The migrational propensity of neuroblastoma is affected by cell identity, but the mechanisms behind the divergence remain unknown. Using RNAi and time-lapse imaging, we show that ADRN-type NB cells exhibit RAC1- and kalirin-dependent nucleokinetic (NUC) migration that relies on several integral comp...
Autores principales: | Afanasyeva, Elena A, Gartlgruber, Moritz, Ryl, Tatsiana, Decaesteker, Bieke, Denecker, Geertrui, Mönke, Gregor, Toprak, Umut H, Florez, Andres, Torkov, Alica, Dreidax, Daniel, Herrmann, Carl, Okonechnikov, Konstantin, Ek, Sara, Sharma, Ashwini Kumar, Sagulenko, Vitaliya, Speleman, Frank, Henrich, Kai-Oliver, Westermann, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017594/ https://www.ncbi.nlm.nih.gov/pubmed/33658318 http://dx.doi.org/10.26508/lsa.201900332 |
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