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The development of an effective synthetic route of rilpivirine
BACKGROUND: Rilpivirine (RPV) was approved by the U.S. FDA (Food and Drug Administration) in 2011 to treat individuals infected with human immunodeficiency virus 1 (HIV-1). Significantly, rilpivirine is three fold more potent than etravirine. Once-daily, it is used with a low oral dose (25 mg/tablet...
Autores principales: | Zhang, Tao, Yang, Jiapei, Zhou, Zhongxia, Fu, Zhipeng, Cherukupalli, Srinivasulu, Kang, Dongwei, Zhan, Peng, Liu, Xinyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017658/ https://www.ncbi.nlm.nih.gov/pubmed/33810807 http://dx.doi.org/10.1186/s13065-021-00749-y |
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