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Microglia Activation in Basal Ganglia Is a Late Event in Huntington Disease Pathophysiology

OBJECTIVE: To define the role played by microglia in different stages of Huntington disease (HD), we used the TSPO radioligand [11C]-ER176 and PET to evaluate microglial activation in relation to neurodegeneration and in relation to the clinical features seen at premanifest and manifest stages of th...

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Detalles Bibliográficos
Autores principales:	Rocha, Natalia P., Charron, Odelin, Latham, Leigh B., Colpo, Gabriela D., Zanotti-Fregonara, Paolo, Yu, Meixiang, Freeman, Leorah, Furr Stimming, Erin, Teixeira, Antonio L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017723/ https://www.ncbi.nlm.nih.gov/pubmed/33795375 http://dx.doi.org/10.1212/NXI.0000000000000984

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