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Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests
Asymptomatic surveillance testing together with COVID-19-related research can lead to positive SARS-CoV-2 tests resulting not from true infections, but non-infectious, non-hazardous by-products of research (amplicons). Amplicons can be widespread and persistent in lab environments and can be difficu...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017732/ https://www.ncbi.nlm.nih.gov/pubmed/34235497 http://dx.doi.org/10.1016/j.crmeth.2021.100005 |
| _version_ | 1783674104541347840 |
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| author | Davidi, Dan Fitzgerald, Susan Glaspell, Hannah L. Jalbert, Samantha Klapperich, Catherine M. Landaverde, Lena Maheras, Stylianos Mattoon, Stephanie E. Britto, Vanessa M. Nguyen, Giang T. Platt, Judy T. Kuhfeldt, Kayla Landsberg, Hannah Stuopis, Cecilia W. Turse, Joshua E. Hamer, Davidson H. Springer, Michael |
| author_facet | Davidi, Dan Fitzgerald, Susan Glaspell, Hannah L. Jalbert, Samantha Klapperich, Catherine M. Landaverde, Lena Maheras, Stylianos Mattoon, Stephanie E. Britto, Vanessa M. Nguyen, Giang T. Platt, Judy T. Kuhfeldt, Kayla Landsberg, Hannah Stuopis, Cecilia W. Turse, Joshua E. Hamer, Davidson H. Springer, Michael |
| author_sort | Davidi, Dan |
| collection | PubMed |
| description | Asymptomatic surveillance testing together with COVID-19-related research can lead to positive SARS-CoV-2 tests resulting not from true infections, but non-infectious, non-hazardous by-products of research (amplicons). Amplicons can be widespread and persistent in lab environments and can be difficult to distinguish for true infections. We discuss prevention and mitigation strategies. |
| format | Online Article Text |
| id | pubmed-8017732 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-80177322021-04-02 Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests Davidi, Dan Fitzgerald, Susan Glaspell, Hannah L. Jalbert, Samantha Klapperich, Catherine M. Landaverde, Lena Maheras, Stylianos Mattoon, Stephanie E. Britto, Vanessa M. Nguyen, Giang T. Platt, Judy T. Kuhfeldt, Kayla Landsberg, Hannah Stuopis, Cecilia W. Turse, Joshua E. Hamer, Davidson H. Springer, Michael Cell Rep Methods Commentary Asymptomatic surveillance testing together with COVID-19-related research can lead to positive SARS-CoV-2 tests resulting not from true infections, but non-infectious, non-hazardous by-products of research (amplicons). Amplicons can be widespread and persistent in lab environments and can be difficult to distinguish for true infections. We discuss prevention and mitigation strategies. Elsevier 2021-04-02 /pmc/articles/PMC8017732/ /pubmed/34235497 http://dx.doi.org/10.1016/j.crmeth.2021.100005 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Commentary Davidi, Dan Fitzgerald, Susan Glaspell, Hannah L. Jalbert, Samantha Klapperich, Catherine M. Landaverde, Lena Maheras, Stylianos Mattoon, Stephanie E. Britto, Vanessa M. Nguyen, Giang T. Platt, Judy T. Kuhfeldt, Kayla Landsberg, Hannah Stuopis, Cecilia W. Turse, Joshua E. Hamer, Davidson H. Springer, Michael Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests |
| title | Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests |
| title_full | Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests |
| title_fullStr | Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests |
| title_full_unstemmed | Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests |
| title_short | Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests |
| title_sort | amplicon residues in research laboratories masquerade as covid-19 in surveillance tests |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017732/ https://www.ncbi.nlm.nih.gov/pubmed/34235497 http://dx.doi.org/10.1016/j.crmeth.2021.100005 |
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