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ABT-263 enhanced bacterial phagocytosis of macrophages in aged mouse through Beclin-1-dependent autophagy

BACKGROUND: Sepsis is a critical challenge for the older adults as the immune function is less responsive by aging. Although cell numbers seem preserved in the older adults, macrophages present age-related function decline, which including reduced chemokines, phagocytosis, and autophagy. ABT-263, an...

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Detalles Bibliográficos
Autores principales:	Zhang, Yu, Tang, Li-hua, Lu, Jia, Xu, Li-ming, Cheng, Bao-li, Xiong, Jun-yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017763/ https://www.ncbi.nlm.nih.gov/pubmed/33794800 http://dx.doi.org/10.1186/s12877-021-02173-2

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