Evaluation of circulating cell-free DNA in cholestatic liver disease using liver-specific methylation markers

BACKGROUND: Quantification of circulating organ-specific cell-free DNA (cfDNA) provides a sensitive measure of ongoing cell death that could benefit evaluation of the cholestatic liver diseases primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), which lack reliable non-invasi...

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Detalles Bibliográficos
Autores principales: Punia, Sohan, Juran, Brian D., Ali, Ahmad H., Schlicht, Erik M., Moore, Raymond M., Sun, Zhifu, Lazaridis, Konstantinos N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017778/
https://www.ncbi.nlm.nih.gov/pubmed/33794792
http://dx.doi.org/10.1186/s12876-021-01741-5

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