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An mtDNA mutant mouse demonstrates that mitochondrial deficiency can result in autism endophenotypes

Autism spectrum disorders (ASDs) are characterized by a deficit in social communication, pathologic repetitive behaviors, restricted interests, and electroencephalogram (EEG) aberrations. While exhaustive analysis of nuclear DNA (nDNA) variation has revealed hundreds of copy number variants (CNVs) a...

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Detalles Bibliográficos
Autores principales:	Yardeni, Tal, Cristancho, Ana G., McCoy, Almedia J., Schaefer, Patrick M., McManus, Meagan J., Marsh, Eric D., Wallace, Douglas C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017921/ https://www.ncbi.nlm.nih.gov/pubmed/33536343 http://dx.doi.org/10.1073/pnas.2021429118

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