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Consequences of aneuploidy in human fibroblasts with trisomy 21

An extra copy of chromosome 21 causes Down syndrome, the most common genetic disease in humans. The mechanisms contributing to aneuploidy-related pathologies in this syndrome, independent of the identity of the triplicated genes, are not well defined. To characterize aneuploidy-driven phenotypes in...

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Detalles Bibliográficos
Autores principales:	Hwang, Sunyoung, Cavaliere, Paola, Li, Rui, Zhu, Lihua Julie, Dephoure, Noah, Torres, Eduardo M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017964/ https://www.ncbi.nlm.nih.gov/pubmed/33526671 http://dx.doi.org/10.1073/pnas.2014723118

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