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Isoform‐specific upregulation of FynT kinase expression is associated with tauopathy and glial activation in Alzheimer's disease and Lewy body dementias

Cumulative data suggest the involvement of Fyn tyrosine kinase in Alzheimer's disease (AD). Previously, our group has shown increased immunoreactivities of the FynT isoform in AD neocortex (with no change in the alternatively spliced FynB isoform) which associated with neurofibrillary degenerat...

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Detalles Bibliográficos
Autores principales: Low, Clara Y. B., Lee, Jasinda H., Lim, Frances T. W., Lee, Chingli, Ballard, Clive, Francis, Paul T., Lai, Mitchell K. P., Tan, Michelle G. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017997/
https://www.ncbi.nlm.nih.gov/pubmed/33128789
http://dx.doi.org/10.1111/bpa.12917