Genetic lesions in MYC and STAT3 drive oncogenic transcription factor overexpression in plasmablastic lymphoma

The mutational profile of plasmablastic lymphoma has not been described. We performed a targeted, exonic next-generation sequencing analysis of 30 plasmablastic lymphoma cases with a Bcell lymphoma-dedicated panel and fluorescence in situ hybridization for the detection of MYC rearrangements. Comple...

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Detalles Bibliográficos
Autores principales: Garcia-Reyero, Julia, Magunacelaya, Nerea Martinez, de Villambrosia, Sonia Gonzalez, Loghavi, Sanam, Mediavilla, Angela Gomez, Tonda, Raul, Beltran, Sergi, Gut, Marta, Gonzalez, Ainara Pereña, D’Ámore, Emmanuel, Visco, Carlo, Khoury, Joseph D., Montes-Moreno, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018103/
https://www.ncbi.nlm.nih.gov/pubmed/32273478
http://dx.doi.org/10.3324/haematol.2020.251579

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