Phase II-like murine trial identifies synergy between dexamethasone and dasatinib in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is frequently characterized by glucocorticoid (GC) resistance, which is associated with inferior outcomes, thus highlighting the need for novel therapeutic approaches for GC-resistant T-ALL. The pre-T-cell receptor (pTCR)/TCR signaling pathways play a crit...

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Detalles Bibliográficos
Autores principales: Shi, Yuzhe, Beckett, Melanie C., Blair, Helen J., Tirtakusuma, Ricky, Nakjang, Sirintra, Enshaei, Amir, Halsey, Christina, Vormoor, Josef, Heidenreich, Olaf, Krippner-Heidenreich, Anja, van Delft, Frederik W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018112/
https://www.ncbi.nlm.nih.gov/pubmed/32139432
http://dx.doi.org/10.3324/haematol.2019.241026

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