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A Case of Sarcoidosis Mimicking Lymphoma Confounded by Cognitive Decline

Sarcoidosis is a disease with an unknown cause that affects multiple organ systems and has a varied clinical presentation. Often, its symptomatology mimics other disease processes, such as lymphoma, tuberculosis, and amyloidosis. The reticuloendothelial involvement and typical B symptoms of weight l...

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Autores principales: Bryant, Benjamin S, Marsh, Kathleen A, Beuerlein, William J, Kalil, Darryl, Shah, Kinchit K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018181/
https://www.ncbi.nlm.nih.gov/pubmed/33824818
http://dx.doi.org/10.7759/cureus.13667
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author Bryant, Benjamin S
Marsh, Kathleen A
Beuerlein, William J
Kalil, Darryl
Shah, Kinchit K
author_facet Bryant, Benjamin S
Marsh, Kathleen A
Beuerlein, William J
Kalil, Darryl
Shah, Kinchit K
author_sort Bryant, Benjamin S
collection PubMed
description Sarcoidosis is a disease with an unknown cause that affects multiple organ systems and has a varied clinical presentation. Often, its symptomatology mimics other disease processes, such as lymphoma, tuberculosis, and amyloidosis. The reticuloendothelial involvement and typical B symptoms of weight loss, fatigue, night sweats, and lymphadenopathy can make sarcoidosis often easily confused with lymphoma. Sarcoidosis has a myriad of central nervous system (CNS) effects, which are often not recognized as symptoms of the disease. These neuropsychiatric symptoms can include, but are not limited to, cognitive decline, headaches, and personality changes. In this report, we discuss a case of a patient who presented with symptoms consistent with indolent lymphoma but was eventually diagnosed with sarcoidosis with extrapulmonary manifestations.
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spelling pubmed-80181812021-04-05 A Case of Sarcoidosis Mimicking Lymphoma Confounded by Cognitive Decline Bryant, Benjamin S Marsh, Kathleen A Beuerlein, William J Kalil, Darryl Shah, Kinchit K Cureus Internal Medicine Sarcoidosis is a disease with an unknown cause that affects multiple organ systems and has a varied clinical presentation. Often, its symptomatology mimics other disease processes, such as lymphoma, tuberculosis, and amyloidosis. The reticuloendothelial involvement and typical B symptoms of weight loss, fatigue, night sweats, and lymphadenopathy can make sarcoidosis often easily confused with lymphoma. Sarcoidosis has a myriad of central nervous system (CNS) effects, which are often not recognized as symptoms of the disease. These neuropsychiatric symptoms can include, but are not limited to, cognitive decline, headaches, and personality changes. In this report, we discuss a case of a patient who presented with symptoms consistent with indolent lymphoma but was eventually diagnosed with sarcoidosis with extrapulmonary manifestations. Cureus 2021-03-03 /pmc/articles/PMC8018181/ /pubmed/33824818 http://dx.doi.org/10.7759/cureus.13667 Text en Copyright © 2021, Bryant et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Bryant, Benjamin S
Marsh, Kathleen A
Beuerlein, William J
Kalil, Darryl
Shah, Kinchit K
A Case of Sarcoidosis Mimicking Lymphoma Confounded by Cognitive Decline
title A Case of Sarcoidosis Mimicking Lymphoma Confounded by Cognitive Decline
title_full A Case of Sarcoidosis Mimicking Lymphoma Confounded by Cognitive Decline
title_fullStr A Case of Sarcoidosis Mimicking Lymphoma Confounded by Cognitive Decline
title_full_unstemmed A Case of Sarcoidosis Mimicking Lymphoma Confounded by Cognitive Decline
title_short A Case of Sarcoidosis Mimicking Lymphoma Confounded by Cognitive Decline
title_sort case of sarcoidosis mimicking lymphoma confounded by cognitive decline
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018181/
https://www.ncbi.nlm.nih.gov/pubmed/33824818
http://dx.doi.org/10.7759/cureus.13667
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