Evaluation of the Pharmacophoric Role of the O–O Bond in Synthetic Antileishmanial Compounds: Comparison between 1,2-Dioxanes and Tetrahydropyrans

[Image: see text] Leishmaniases are neglected diseases that can be treated with a limited drug arsenal; the development of new molecules is therefore a priority. Recent evidence indicates that endoperoxides, including artemisinin and its derivatives, possess antileishmanial activity. Here, 1,2-dioxa...

Descripción completa

Detalles Bibliográficos
Autores principales: Ortalli, Margherita, Varani, Stefania, Cimato, Giorgia, Veronesi, Ruben, Quintavalla, Arianna, Lombardo, Marco, Monari, Magda, Trombini, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018184/
https://www.ncbi.nlm.nih.gov/pubmed/33091297
http://dx.doi.org/10.1021/acs.jmedchem.0c01589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018184/
https://www.ncbi.nlm.nih.gov/pubmed/33091297
http://dx.doi.org/10.1021/acs.jmedchem.0c01589

Ejemplares similares