Cargando…

COVID-19 simulation study—the effect of strict non-pharmaceutical interventions (NPIs) on controlling the spread of COVID-19

BACKGROUND: From the beginning of 2020, COVID-19 infection has changed our lives in many aspects and introduced limitations in the way people interact and communicate. In this paper, we are evaluating the effect of non-pharmaceutical interventions (NPI) in limiting the spread of the Severe Acute Res...

Descripción completa

Detalles Bibliográficos
Autores principales: Alzu’bi, Amal, Abu Alasal, Sanaa, Kheirallah, Khalid A., Watzlaf, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018247/
https://www.ncbi.nlm.nih.gov/pubmed/33850666
http://dx.doi.org/10.7717/peerj.11172
_version_ 1783674177293647872
author Alzu’bi, Amal
Abu Alasal, Sanaa
Kheirallah, Khalid A.
Watzlaf, Valerie
author_facet Alzu’bi, Amal
Abu Alasal, Sanaa
Kheirallah, Khalid A.
Watzlaf, Valerie
author_sort Alzu’bi, Amal
collection PubMed
description BACKGROUND: From the beginning of 2020, COVID-19 infection has changed our lives in many aspects and introduced limitations in the way people interact and communicate. In this paper, we are evaluating the effect of non-pharmaceutical interventions (NPI) in limiting the spread of the Severe Acute Respiratory Syndrome Coronavirus 2 pandemic during a wedding ceremony from Irbid, Northern Jordan. Agent-based modeling was used in a real wedding event that occurred at the beginning of the spread of the pandemic in Jordan. Two infected nationals of Jordan, who arrived in Jordan about a week before the event, initiated the spread of the pandemic within the contact community. METHODS: In this work, a strict national NPI that the government implemented is developed by using an abstract model with certain characteristics similar to the Jordanian community. Thus, the Jordanian community is represented in terms of ages, occupations, and population movements. After that, the extent of the impact of the NPI measures on the local community is measured. RESULTS: We observed the deterioration of the state of society while the epidemic is spreading among individuals in the absence of preventive measures. Also, the results show that the herd immunity case was an epidemic, with a high level of spread among the community with 918 cases during a short interval of time. On the other hand, the preventive measures scenario shows a totally controlled spread with only 74 cases applied on the same interval of time. Furthermore, a convergence in the actual results of the real system with the hypothetical system were detected in the case of applying the strict NPI measures. Finally, strict NPI at the community level following social gatherings seem to be effective measures to control the spread of the COVID- 19 pandemic.
format Online
Article
Text
id pubmed-8018247
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher PeerJ Inc.
record_format MEDLINE/PubMed
spelling pubmed-80182472021-04-12 COVID-19 simulation study—the effect of strict non-pharmaceutical interventions (NPIs) on controlling the spread of COVID-19 Alzu’bi, Amal Abu Alasal, Sanaa Kheirallah, Khalid A. Watzlaf, Valerie PeerJ Infectious Diseases BACKGROUND: From the beginning of 2020, COVID-19 infection has changed our lives in many aspects and introduced limitations in the way people interact and communicate. In this paper, we are evaluating the effect of non-pharmaceutical interventions (NPI) in limiting the spread of the Severe Acute Respiratory Syndrome Coronavirus 2 pandemic during a wedding ceremony from Irbid, Northern Jordan. Agent-based modeling was used in a real wedding event that occurred at the beginning of the spread of the pandemic in Jordan. Two infected nationals of Jordan, who arrived in Jordan about a week before the event, initiated the spread of the pandemic within the contact community. METHODS: In this work, a strict national NPI that the government implemented is developed by using an abstract model with certain characteristics similar to the Jordanian community. Thus, the Jordanian community is represented in terms of ages, occupations, and population movements. After that, the extent of the impact of the NPI measures on the local community is measured. RESULTS: We observed the deterioration of the state of society while the epidemic is spreading among individuals in the absence of preventive measures. Also, the results show that the herd immunity case was an epidemic, with a high level of spread among the community with 918 cases during a short interval of time. On the other hand, the preventive measures scenario shows a totally controlled spread with only 74 cases applied on the same interval of time. Furthermore, a convergence in the actual results of the real system with the hypothetical system were detected in the case of applying the strict NPI measures. Finally, strict NPI at the community level following social gatherings seem to be effective measures to control the spread of the COVID- 19 pandemic. PeerJ Inc. 2021-03-30 /pmc/articles/PMC8018247/ /pubmed/33850666 http://dx.doi.org/10.7717/peerj.11172 Text en © 2021 Alzu’bi et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Infectious Diseases
Alzu’bi, Amal
Abu Alasal, Sanaa
Kheirallah, Khalid A.
Watzlaf, Valerie
COVID-19 simulation study—the effect of strict non-pharmaceutical interventions (NPIs) on controlling the spread of COVID-19
title COVID-19 simulation study—the effect of strict non-pharmaceutical interventions (NPIs) on controlling the spread of COVID-19
title_full COVID-19 simulation study—the effect of strict non-pharmaceutical interventions (NPIs) on controlling the spread of COVID-19
title_fullStr COVID-19 simulation study—the effect of strict non-pharmaceutical interventions (NPIs) on controlling the spread of COVID-19
title_full_unstemmed COVID-19 simulation study—the effect of strict non-pharmaceutical interventions (NPIs) on controlling the spread of COVID-19
title_short COVID-19 simulation study—the effect of strict non-pharmaceutical interventions (NPIs) on controlling the spread of COVID-19
title_sort covid-19 simulation study—the effect of strict non-pharmaceutical interventions (npis) on controlling the spread of covid-19
topic Infectious Diseases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018247/
https://www.ncbi.nlm.nih.gov/pubmed/33850666
http://dx.doi.org/10.7717/peerj.11172
work_keys_str_mv AT alzubiamal covid19simulationstudytheeffectofstrictnonpharmaceuticalinterventionsnpisoncontrollingthespreadofcovid19
AT abualasalsanaa covid19simulationstudytheeffectofstrictnonpharmaceuticalinterventionsnpisoncontrollingthespreadofcovid19
AT kheirallahkhalida covid19simulationstudytheeffectofstrictnonpharmaceuticalinterventionsnpisoncontrollingthespreadofcovid19
AT watzlafvalerie covid19simulationstudytheeffectofstrictnonpharmaceuticalinterventionsnpisoncontrollingthespreadofcovid19