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KRAS‐Mutated, Estrogen Receptor‐Positive Low‐Grade Serous Ovarian Cancer: Unraveling an Exceptional Response Mystery
We report on a woman with aggressive estrogen receptor‐positive, KRAS‐mutated ovarian cancer who achieved a remarkable response to combination therapy with the MEK inhibitor (trametinib) and the aromatase inhibitor (letrozole), even though the disease had failed to respond to a combination of a PI3K...
Autores principales: | Kato, Shumei, McFall, Thomas, Takahashi, Kenta, Bamel, Kasey, Ikeda, Sadakatsu, Eskander, Ramez N., Plaxe, Steven, Parker, Barbara, Stites, Edward, Kurzrock, Razelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018312/ https://www.ncbi.nlm.nih.gov/pubmed/33528846 http://dx.doi.org/10.1002/onco.13702 |
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