A JAK of all trades: how global phosphoproteomics reveal the Achilles heel of MPNs

While Janus-kinase (JAK)-inhibitors effectively reduce the inflammatory phenotype of myeloproliferative neoplasms (MPN), they do not affect disease burden or presence of the mutated clone to a major extent. Here, we show how Janus-kinase 2 (JAK2)-mutated cells persist through maintenance of the mito...

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Detalles Bibliográficos
Autores principales: Schnoeder, Tina M., Perner, Florian, Heidel, Florian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018336/
https://www.ncbi.nlm.nih.gov/pubmed/33855167
http://dx.doi.org/10.1080/23723556.2020.1871172

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