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Control of S phase duration: a replication capacity model with E2F transcription at its heart
DNA replication capacity, the maximal amount of DNA a cell can synthesize at any given time during S phase, is controlled by E2F-dependent transcription. Controlling replication capacity limits the replication rate and provides a robust mechanism to keep replication fork speed within an optimal rang...
Autores principales: | Bertoli, Cosetta, de Bruin, Robertus A.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018357/ https://www.ncbi.nlm.nih.gov/pubmed/33855165 http://dx.doi.org/10.1080/23723556.2020.1839294 |
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