Mechanical softness: a true stemness feature for cancer cells

Developing a method that can effectively define and sort cancer stem cells (CSCs) is extremely desirable. Mechanical stiffness is of paramount importance for a cell to differentiate and can reflect the differentiation state of cells. In line with this notion, cell softness is identified to be a uniq...

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Detalles Bibliográficos
Autores principales: Lv, Jiadi, Liu, Yuying, Huang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018513/
https://www.ncbi.nlm.nih.gov/pubmed/33855168
http://dx.doi.org/10.1080/23723556.2021.1882285
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author Lv, Jiadi
Liu, Yuying
Huang, Bo
author_facet Lv, Jiadi
Liu, Yuying
Huang, Bo
author_sort Lv, Jiadi
collection PubMed
description Developing a method that can effectively define and sort cancer stem cells (CSCs) is extremely desirable. Mechanical stiffness is of paramount importance for a cell to differentiate and can reflect the differentiation state of cells. In line with this notion, cell softness is identified to be a unique marker for highly tumorigenic CSCs.
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spelling pubmed-80185132021-04-13 Mechanical softness: a true stemness feature for cancer cells Lv, Jiadi Liu, Yuying Huang, Bo Mol Cell Oncol Commentary Developing a method that can effectively define and sort cancer stem cells (CSCs) is extremely desirable. Mechanical stiffness is of paramount importance for a cell to differentiate and can reflect the differentiation state of cells. In line with this notion, cell softness is identified to be a unique marker for highly tumorigenic CSCs. Taylor & Francis 2021-02-16 /pmc/articles/PMC8018513/ /pubmed/33855168 http://dx.doi.org/10.1080/23723556.2021.1882285 Text en © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Commentary
Lv, Jiadi
Liu, Yuying
Huang, Bo
Mechanical softness: a true stemness feature for cancer cells
title Mechanical softness: a true stemness feature for cancer cells
title_full Mechanical softness: a true stemness feature for cancer cells
title_fullStr Mechanical softness: a true stemness feature for cancer cells
title_full_unstemmed Mechanical softness: a true stemness feature for cancer cells
title_short Mechanical softness: a true stemness feature for cancer cells
title_sort mechanical softness: a true stemness feature for cancer cells
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018513/
https://www.ncbi.nlm.nih.gov/pubmed/33855168
http://dx.doi.org/10.1080/23723556.2021.1882285
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