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Constitutive Activation of the B Cell Receptor Underlies Dysfunctional Signaling in Chronic Lymphocytic Leukemia

In cancer biology, the functional interpretation of genomic alterations is critical to achieve the promise of genomic profiling in the clinic. For chronic lymphocytic leukemia (CLL), a heterogeneous disease of B-lymphocytes maturing under constitutive B cell receptor (BCR) stimulation, the functiona...

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Detalles Bibliográficos
Autores principales:	Ziegler, Carly G.K., Kim, Joel, Piersanti, Kelly, Oyler-Yaniv, Alon, Argyropoulos, Kimon V., van den Brink, Marcel R.M., Palomba, M. Lia, Altan-Bonnet, Nihal, Altan-Bonnet, Grégoire
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018719/ https://www.ncbi.nlm.nih.gov/pubmed/31340154 http://dx.doi.org/10.1016/j.celrep.2019.06.069

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