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Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells
The blood-brain barrier (BBB) is one of the main obstacles for therapies targeting brain diseases. Most macromolecules fail to pass the tight BBB, formed by brain endothelial cells interlinked by tight junctions. A wide range of small, lipid-soluble molecules can enter the brain parenchyma via diffu...
Autores principales: | Hudecz, Diána, Sigurdardóttir, Sara Björk, Christensen, Sarah Christine, Hempel, Casper, Urquhart, Andrew J., Andresen, Thomas Lars, Nielsen, Morten S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018780/ https://www.ncbi.nlm.nih.gov/pubmed/33798235 http://dx.doi.org/10.1371/journal.pone.0249686 |
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