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Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States
The emergence and spread of SARS-CoV-2 lineage B.1.1.7, first detected in the United Kingdom, has become a global public health concern because of its increased transmissibility. Over 2,500 COVID-19 cases associated with this variant have been detected in the United States (US) since December 2020,...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018830/ https://www.ncbi.nlm.nih.gov/pubmed/33891875 http://dx.doi.org/10.1016/j.cell.2021.03.061 |
| _version_ | 1783674258693554176 |
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| author | Alpert, Tara Brito, Anderson F. Lasek-Nesselquist, Erica Rothman, Jessica Valesano, Andrew L. MacKay, Matthew J. Petrone, Mary E. Breban, Mallery I. Watkins, Anne E. Vogels, Chantal B.F. Kalinich, Chaney C. Dellicour, Simon Russell, Alexis Kelly, John P. Shudt, Matthew Plitnick, Jonathan Schneider, Erasmus Fitzsimmons, William J. Khullar, Gaurav Metti, Jessica Dudley, Joel T. Nash, Megan Beaubier, Nike Wang, Jianhui Liu, Chen Hui, Pei Muyombwe, Anthony Downing, Randy Razeq, Jafar Bart, Stephen M. Grills, Ardath Morrison, Stephanie M. Murphy, Steven Neal, Caleb Laszlo, Eva Rennert, Hanna Cushing, Melissa Westblade, Lars Velu, Priya Craney, Arryn Cong, Lin Peaper, David R. Landry, Marie L. Cook, Peter W. Fauver, Joseph R. Mason, Christopher E. Lauring, Adam S. St. George, Kirsten MacCannell, Duncan R. Grubaugh, Nathan D. |
| author_facet | Alpert, Tara Brito, Anderson F. Lasek-Nesselquist, Erica Rothman, Jessica Valesano, Andrew L. MacKay, Matthew J. Petrone, Mary E. Breban, Mallery I. Watkins, Anne E. Vogels, Chantal B.F. Kalinich, Chaney C. Dellicour, Simon Russell, Alexis Kelly, John P. Shudt, Matthew Plitnick, Jonathan Schneider, Erasmus Fitzsimmons, William J. Khullar, Gaurav Metti, Jessica Dudley, Joel T. Nash, Megan Beaubier, Nike Wang, Jianhui Liu, Chen Hui, Pei Muyombwe, Anthony Downing, Randy Razeq, Jafar Bart, Stephen M. Grills, Ardath Morrison, Stephanie M. Murphy, Steven Neal, Caleb Laszlo, Eva Rennert, Hanna Cushing, Melissa Westblade, Lars Velu, Priya Craney, Arryn Cong, Lin Peaper, David R. Landry, Marie L. Cook, Peter W. Fauver, Joseph R. Mason, Christopher E. Lauring, Adam S. St. George, Kirsten MacCannell, Duncan R. Grubaugh, Nathan D. |
| author_sort | Alpert, Tara |
| collection | PubMed |
| description | The emergence and spread of SARS-CoV-2 lineage B.1.1.7, first detected in the United Kingdom, has become a global public health concern because of its increased transmissibility. Over 2,500 COVID-19 cases associated with this variant have been detected in the United States (US) since December 2020, but the extent of establishment is relatively unknown. Using travel, genomic, and diagnostic data, we highlight that the primary ports of entry for B.1.1.7 in the US were in New York, California, and Florida. Furthermore, we found evidence for many independent B.1.1.7 establishments starting in early December 2020, followed by interstate spread by the end of the month. Finally, we project that B.1.1.7 will be the dominant lineage in many states by mid- to late March. Thus, genomic surveillance for B.1.1.7 and other variants urgently needs to be enhanced to better inform the public health response. |
| format | Online Article Text |
| id | pubmed-8018830 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Elsevier Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-80188302021-04-06 Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States Alpert, Tara Brito, Anderson F. Lasek-Nesselquist, Erica Rothman, Jessica Valesano, Andrew L. MacKay, Matthew J. Petrone, Mary E. Breban, Mallery I. Watkins, Anne E. Vogels, Chantal B.F. Kalinich, Chaney C. Dellicour, Simon Russell, Alexis Kelly, John P. Shudt, Matthew Plitnick, Jonathan Schneider, Erasmus Fitzsimmons, William J. Khullar, Gaurav Metti, Jessica Dudley, Joel T. Nash, Megan Beaubier, Nike Wang, Jianhui Liu, Chen Hui, Pei Muyombwe, Anthony Downing, Randy Razeq, Jafar Bart, Stephen M. Grills, Ardath Morrison, Stephanie M. Murphy, Steven Neal, Caleb Laszlo, Eva Rennert, Hanna Cushing, Melissa Westblade, Lars Velu, Priya Craney, Arryn Cong, Lin Peaper, David R. Landry, Marie L. Cook, Peter W. Fauver, Joseph R. Mason, Christopher E. Lauring, Adam S. St. George, Kirsten MacCannell, Duncan R. Grubaugh, Nathan D. Cell Article The emergence and spread of SARS-CoV-2 lineage B.1.1.7, first detected in the United Kingdom, has become a global public health concern because of its increased transmissibility. Over 2,500 COVID-19 cases associated with this variant have been detected in the United States (US) since December 2020, but the extent of establishment is relatively unknown. Using travel, genomic, and diagnostic data, we highlight that the primary ports of entry for B.1.1.7 in the US were in New York, California, and Florida. Furthermore, we found evidence for many independent B.1.1.7 establishments starting in early December 2020, followed by interstate spread by the end of the month. Finally, we project that B.1.1.7 will be the dominant lineage in many states by mid- to late March. Thus, genomic surveillance for B.1.1.7 and other variants urgently needs to be enhanced to better inform the public health response. Elsevier Inc. 2021-05-13 2021-04-03 /pmc/articles/PMC8018830/ /pubmed/33891875 http://dx.doi.org/10.1016/j.cell.2021.03.061 Text en © 2021 Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
| spellingShingle | Article Alpert, Tara Brito, Anderson F. Lasek-Nesselquist, Erica Rothman, Jessica Valesano, Andrew L. MacKay, Matthew J. Petrone, Mary E. Breban, Mallery I. Watkins, Anne E. Vogels, Chantal B.F. Kalinich, Chaney C. Dellicour, Simon Russell, Alexis Kelly, John P. Shudt, Matthew Plitnick, Jonathan Schneider, Erasmus Fitzsimmons, William J. Khullar, Gaurav Metti, Jessica Dudley, Joel T. Nash, Megan Beaubier, Nike Wang, Jianhui Liu, Chen Hui, Pei Muyombwe, Anthony Downing, Randy Razeq, Jafar Bart, Stephen M. Grills, Ardath Morrison, Stephanie M. Murphy, Steven Neal, Caleb Laszlo, Eva Rennert, Hanna Cushing, Melissa Westblade, Lars Velu, Priya Craney, Arryn Cong, Lin Peaper, David R. Landry, Marie L. Cook, Peter W. Fauver, Joseph R. Mason, Christopher E. Lauring, Adam S. St. George, Kirsten MacCannell, Duncan R. Grubaugh, Nathan D. Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States |
| title | Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States |
| title_full | Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States |
| title_fullStr | Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States |
| title_full_unstemmed | Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States |
| title_short | Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States |
| title_sort | early introductions and transmission of sars-cov-2 variant b.1.1.7 in the united states |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018830/ https://www.ncbi.nlm.nih.gov/pubmed/33891875 http://dx.doi.org/10.1016/j.cell.2021.03.061 |
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