Interactive tool to create adjustable anatomical atlases for mouse brain imaging

OBJECTIVE: Brain atlases are important research tools enabling researchers to focus their investigations on specific anatomically defined brain regions and are used in many MRI applications, e.g. in fMRI, morphometry, whole brain spectroscopy, et cetera. Despite their extensive use and numerous vers...

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Autores principales: Sack, Markus, Zheng, Lei, Gass, Natalia, Ende, Gabriele, Sartorius, Alexander, Weber-Fahr, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018930/
https://www.ncbi.nlm.nih.gov/pubmed/32696290
http://dx.doi.org/10.1007/s10334-020-00866-0
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author Sack, Markus
Zheng, Lei
Gass, Natalia
Ende, Gabriele
Sartorius, Alexander
Weber-Fahr, Wolfgang
author_facet Sack, Markus
Zheng, Lei
Gass, Natalia
Ende, Gabriele
Sartorius, Alexander
Weber-Fahr, Wolfgang
author_sort Sack, Markus
collection PubMed
description OBJECTIVE: Brain atlases are important research tools enabling researchers to focus their investigations on specific anatomically defined brain regions and are used in many MRI applications, e.g. in fMRI, morphometry, whole brain spectroscopy, et cetera. Despite their extensive use and numerous versions they usually consist of predefined rigid brain regions with a given level of detail often degrading them to a non-ideal tool in special research topics. RESULT: To overcome this intrinsic weakness we present a graphical user interface application which allows researchers to easily create mouse brain atlases with an adjustable user-defined level of detail and coverage to match specific research questions.
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spelling pubmed-80189302021-04-16 Interactive tool to create adjustable anatomical atlases for mouse brain imaging Sack, Markus Zheng, Lei Gass, Natalia Ende, Gabriele Sartorius, Alexander Weber-Fahr, Wolfgang MAGMA Research Article OBJECTIVE: Brain atlases are important research tools enabling researchers to focus their investigations on specific anatomically defined brain regions and are used in many MRI applications, e.g. in fMRI, morphometry, whole brain spectroscopy, et cetera. Despite their extensive use and numerous versions they usually consist of predefined rigid brain regions with a given level of detail often degrading them to a non-ideal tool in special research topics. RESULT: To overcome this intrinsic weakness we present a graphical user interface application which allows researchers to easily create mouse brain atlases with an adjustable user-defined level of detail and coverage to match specific research questions. Springer International Publishing 2020-07-21 2021 /pmc/articles/PMC8018930/ /pubmed/32696290 http://dx.doi.org/10.1007/s10334-020-00866-0 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Sack, Markus
Zheng, Lei
Gass, Natalia
Ende, Gabriele
Sartorius, Alexander
Weber-Fahr, Wolfgang
Interactive tool to create adjustable anatomical atlases for mouse brain imaging
title Interactive tool to create adjustable anatomical atlases for mouse brain imaging
title_full Interactive tool to create adjustable anatomical atlases for mouse brain imaging
title_fullStr Interactive tool to create adjustable anatomical atlases for mouse brain imaging
title_full_unstemmed Interactive tool to create adjustable anatomical atlases for mouse brain imaging
title_short Interactive tool to create adjustable anatomical atlases for mouse brain imaging
title_sort interactive tool to create adjustable anatomical atlases for mouse brain imaging
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018930/
https://www.ncbi.nlm.nih.gov/pubmed/32696290
http://dx.doi.org/10.1007/s10334-020-00866-0
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