Directly Reprogrammed Neurons Express MAPT and APP Splice Variants Pertinent to Ageing and Neurodegeneration

Neurons produced by reprogramming of other cell types are used to study cellular mechanisms of age-related neurodegenerative diseases. To model Alzheimer’s disease and other tauopathies, it is essential that alternative splicing of the MAPT transcript in these neurons produces the relevant tau isofo...

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Detalles Bibliográficos
Autores principales: Habekost, Mette, Qvist, Per, Denham, Mark, Holm, Ida E., Jørgensen, Arne Lund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018937/
https://www.ncbi.nlm.nih.gov/pubmed/33415685
http://dx.doi.org/10.1007/s12035-020-02258-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018937/
https://www.ncbi.nlm.nih.gov/pubmed/33415685
http://dx.doi.org/10.1007/s12035-020-02258-w

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