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Clinical predictors for deep vein thrombosis on admission in patients with intertrochanteric fractures: a retrospective study

BACKGROUND: Limited studies were available to investigate the prevalence of deep vein thrombosis (DVT) on admission in elderly patients with intertrochanteric fractures. The aim of present study was to evaluate risk factors and the prevalence of pre-admission DVT in elderly patients with intertrocha...

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Autores principales: Fan, Jixing, Zhou, Fang, Xu, Xiangyu, Zhang, Zhishan, Tian, Yun, Ji, Hongquan, Guo, Yan, Lv, Yang, Yang, Zhongwei, Hou, Guojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019175/
https://www.ncbi.nlm.nih.gov/pubmed/33810786
http://dx.doi.org/10.1186/s12891-021-04196-7
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author Fan, Jixing
Zhou, Fang
Xu, Xiangyu
Zhang, Zhishan
Tian, Yun
Ji, Hongquan
Guo, Yan
Lv, Yang
Yang, Zhongwei
Hou, Guojin
author_facet Fan, Jixing
Zhou, Fang
Xu, Xiangyu
Zhang, Zhishan
Tian, Yun
Ji, Hongquan
Guo, Yan
Lv, Yang
Yang, Zhongwei
Hou, Guojin
author_sort Fan, Jixing
collection PubMed
description BACKGROUND: Limited studies were available to investigate the prevalence of deep vein thrombosis (DVT) on admission in elderly patients with intertrochanteric fractures. The aim of present study was to evaluate risk factors and the prevalence of pre-admission DVT in elderly patients with intertrochanteric fractures. METHODS: This retrospective study included 788 elderly patients with intertrochanteric fracture who were eligible for this study from January 1, 2010, to December 31, 2019. Color doppler ultrasonography was performed for DVT detection at admission. All patients’ clinical data were collected. Univariate analysis and stepwise backward multivariate logistic regression were used to identify the risk factors contributing to the occurrence of DVT. RESULTS: The overall prevalence of pre-admission DVT in patients with intertrochanteric fractures was 20.81% (164 of 788 patients). The mean time from injury to admission was 2.1 days in the total population, 2.96 and 1.87 days in patients with and without DVT. Univariate analysis showed that significantly elevated risk of DVT were found in patients with longer time from injury to admission, high energy injury, lower Hb value, higher BMI, diabetes, chronic obstructive pulmonary disease (COPD), atrial fibrillation, dementia, varicose veins, higher age-adjusted CCI, higher ASA class and A3 type intertrochanteric fractures (P < 0.05). The adjusted multivariate logistic regression analysis demonstrated that longer time from injury to admission, high energy trauma, COPD, lower Hb, diabetes and A3 type intertrochanteric fractures were independent risk factors of pre-admission DVT. CONCLUSIONS: A high prevalence of pre-admission DVT was found in elderly Chinese patients with intertrochanteric fractures. Therefore, surgeons should be aware of the high prevalence of DVT for elderly patients with intertrochanteric fractures in order to prevent intraoperative and postoperative PE and other lethal complications.
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spelling pubmed-80191752021-04-05 Clinical predictors for deep vein thrombosis on admission in patients with intertrochanteric fractures: a retrospective study Fan, Jixing Zhou, Fang Xu, Xiangyu Zhang, Zhishan Tian, Yun Ji, Hongquan Guo, Yan Lv, Yang Yang, Zhongwei Hou, Guojin BMC Musculoskelet Disord Research Article BACKGROUND: Limited studies were available to investigate the prevalence of deep vein thrombosis (DVT) on admission in elderly patients with intertrochanteric fractures. The aim of present study was to evaluate risk factors and the prevalence of pre-admission DVT in elderly patients with intertrochanteric fractures. METHODS: This retrospective study included 788 elderly patients with intertrochanteric fracture who were eligible for this study from January 1, 2010, to December 31, 2019. Color doppler ultrasonography was performed for DVT detection at admission. All patients’ clinical data were collected. Univariate analysis and stepwise backward multivariate logistic regression were used to identify the risk factors contributing to the occurrence of DVT. RESULTS: The overall prevalence of pre-admission DVT in patients with intertrochanteric fractures was 20.81% (164 of 788 patients). The mean time from injury to admission was 2.1 days in the total population, 2.96 and 1.87 days in patients with and without DVT. Univariate analysis showed that significantly elevated risk of DVT were found in patients with longer time from injury to admission, high energy injury, lower Hb value, higher BMI, diabetes, chronic obstructive pulmonary disease (COPD), atrial fibrillation, dementia, varicose veins, higher age-adjusted CCI, higher ASA class and A3 type intertrochanteric fractures (P < 0.05). The adjusted multivariate logistic regression analysis demonstrated that longer time from injury to admission, high energy trauma, COPD, lower Hb, diabetes and A3 type intertrochanteric fractures were independent risk factors of pre-admission DVT. CONCLUSIONS: A high prevalence of pre-admission DVT was found in elderly Chinese patients with intertrochanteric fractures. Therefore, surgeons should be aware of the high prevalence of DVT for elderly patients with intertrochanteric fractures in order to prevent intraoperative and postoperative PE and other lethal complications. BioMed Central 2021-04-02 /pmc/articles/PMC8019175/ /pubmed/33810786 http://dx.doi.org/10.1186/s12891-021-04196-7 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Fan, Jixing
Zhou, Fang
Xu, Xiangyu
Zhang, Zhishan
Tian, Yun
Ji, Hongquan
Guo, Yan
Lv, Yang
Yang, Zhongwei
Hou, Guojin
Clinical predictors for deep vein thrombosis on admission in patients with intertrochanteric fractures: a retrospective study
title Clinical predictors for deep vein thrombosis on admission in patients with intertrochanteric fractures: a retrospective study
title_full Clinical predictors for deep vein thrombosis on admission in patients with intertrochanteric fractures: a retrospective study
title_fullStr Clinical predictors for deep vein thrombosis on admission in patients with intertrochanteric fractures: a retrospective study
title_full_unstemmed Clinical predictors for deep vein thrombosis on admission in patients with intertrochanteric fractures: a retrospective study
title_short Clinical predictors for deep vein thrombosis on admission in patients with intertrochanteric fractures: a retrospective study
title_sort clinical predictors for deep vein thrombosis on admission in patients with intertrochanteric fractures: a retrospective study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019175/
https://www.ncbi.nlm.nih.gov/pubmed/33810786
http://dx.doi.org/10.1186/s12891-021-04196-7
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