Cargando…

Forecasting sensitive targets of the kynurenine pathway in pancreatic adenocarcinoma using mathematical modeling

In this study, a new mathematical model was established and validated to forecast and define sensitive targets in the kynurenine pathway (Kynp) in pancreatic adenocarcinoma (PDAC). Using the Panc‐1 cell line, genetic profiles of Kynp molecules were tested. qPCR data were implemented in the algorithm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alahdal, Murad, Sun, Deshun, Duan, Li, Ouyang, Hongwei, Wang, Manyi, Xiong, Jianyi, Wang, Daping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019197/ https://www.ncbi.nlm.nih.gov/pubmed/33523522 http://dx.doi.org/10.1111/cas.14832

Ejemplares similares

Modeling and forecasting the spread tendency of the COVID-19 in China
por: Sun, Deshun, et al.
Publicado: (2020)

Indoleamine 2, 3 Dioxygenase 1 Impairs Chondrogenic Differentiation of Mesenchymal Stem Cells in the Joint of Osteoarthritis Mice Model
por: Alahdal, Murad, et al.
Publicado: (2021)

Analysis of an improved fractional-order model of boundary formation in the Drosophila large intestine dependent on Delta-Notch pathway
por: Sun, Deshun, et al.
Publicado: (2020)

The Homeostasis of Cartilage Matrix Remodeling and the Regulation of Volume-Sensitive Ion Channel
por: Deng, Zhiqin, et al.
Publicado: (2022)

IRE1 signaling regulates chondrocyte apoptosis and death fate in the osteoarthritis
por: Huang, Rongxiang, et al.
Publicado: (2021)

1-Methyl-D-tryptophan Reduces Tumor CD133(+) cells, Wnt/β-catenin and NF-κβp65 while Enhances Lymphocytes NF-κβ2, STAT3, and STAT4 Pathways in Murine Pancreatic Adenocarcinoma
por: Alahdal, Murad, et al.
Publicado: (2018)

The Kynurenine Pathway and Kynurenine 3-Monooxygenase Inhibitors
por: Hughes, Tamera D., et al.
Publicado: (2022)

Modulation of Enzyme Activity in the Kynurenine Pathway by Kynurenine Monooxygenase Inhibition
por: Phillips, Robert S., et al.
Publicado: (2019)

Cell-to-Cell Culture Inhibits Dedifferentiation of Chondrocytes and Induces Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells
por: Li, Xingfu, et al.
Publicado: (2019)

Imbalanced Kynurenine Pathway in Schizophrenia
por: Kegel, Magdalena E, et al.
Publicado: (2014)

Kynurenine pathway metabolites in migraine
por: Nicoletti, Ferdinando
Publicado: (2015)

Kynurenine pathway in kidney diseases
por: Zakrocka, Izabela, et al.
Publicado: (2021)

High expression of MAPK-14 promoting the death of chondrocytes is an important signal of osteoarthritis process
por: Deng, Zhiqin, et al.
Publicado: (2021)

Screening and verification of hub genes involved in osteoarthritis using bioinformatics
por: Xie, Junxiong, et al.
Publicado: (2021)

The kynurenine pathway is involved in bacterial meningitis
por: Coutinho, Leonam G, et al.
Publicado: (2014)

The Kynurenine Pathway in Stem Cell Biology
por: Jones, Simon P., et al.
Publicado: (2013)

Immunohistochemical Studies of the Kynurenine Pathway in Morphea
por: Noakes, Rowland, et al.
Publicado: (2013)

Kynurenine pathway metabolism and neuroinflammatory disease
por: Braidy, Nady, et al.
Publicado: (2017)

Kynurenine pathway in Parkinson's disease—An update
por: Venkatesan, Dhivya, et al.
Publicado: (2020)

Involvement of Kynurenine Pathway in Hepatocellular Carcinoma
por: Krishnamurthy, Shivani, et al.
Publicado: (2021)

The Footprint of Kynurenine Pathway in Cardiovascular Diseases
por: Ala, Moein, et al.
Publicado: (2022)

The Involvement of Kynurenine Pathway in Neurodegenerative Diseases
por: Martins, Lais B., et al.
Publicado: (2023)

The kynurenine pathway in HIV, frailty and inflammaging
por: Sultana, Shabiha, et al.
Publicado: (2023)

Extracellular matrix production in vitro in cartilage tissue engineering
por: Chen, Jie-Lin, et al.
Publicado: (2014)

Overexpression of ClC-3 Chloride Channel in Chondrosarcoma: An In Vivo Immunohistochemical Study with Tissue Microarray
por: Deng, Zhiqin, et al.
Publicado: (2019)

Kynurenine Pathway Metabolites as Potential Biomarkers in Chronic Pain
por: Auyeung, Andrew, et al.
Publicado: (2023)

Repair of articular cartilage defects with intra-articular injection of autologous rabbit synovial fluid-derived mesenchymal stem cells
por: Jia, Zhaofeng, et al.
Publicado: (2018)

Effects of ATP9A on Extracellular Vesicle Release and Exosomal Lipid Composition
por: Xu, Xiao, et al.
Publicado: (2020)

SARS epidemical forecast research in mathematical model
por: Guanghong, Ding, et al.
Publicado: (2013)

Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Contribute to Chondrogenesis in Coculture with Chondrocytes
por: Li, Xingfu, et al.
Publicado: (2016)

A prospective evaluation of serum kynurenine metabolites and risk of pancreatic cancer
por: Huang, Joyce Y., et al.
Publicado: (2018)

The Involvement of Neuroinflammation and Kynurenine Pathway in Parkinson's Disease
por: Zinger, Anna, et al.
Publicado: (2011)

Involvement of the Kynurenine Pathway in Human Glioma Pathophysiology
por: Adams, Seray, et al.
Publicado: (2014)

Neuroinflammation and the Immune-Kynurenine Pathway in Anxiety Disorders
por: Kim, Yong-Ku, et al.
Publicado: (2018)

Kynurenine Pathway Activation in Human African Trypanosomiasis
por: Sternberg, Jeremy M., et al.
Publicado: (2017)

Kynurenine and Tetrahydrobiopterin Pathways Crosstalk in Pain Hypersensitivity
por: Staats Pires, Ananda, et al.
Publicado: (2020)

The Kynurenine Pathway: A Finger in Every Pie
por: Savitz, Jonathan
Publicado: (2019)

Kynurenine Pathway Metabolites as Biomarkers in Alzheimer's Disease
por: Liang, Yuqing, et al.
Publicado: (2022)

The kynurenine pathway in traumatic brain injuries and concussion
por: Dehhaghi, Mona, et al.
Publicado: (2023)

The tryptophan–kynurenine pathway in immunomodulation and cancer metastasis
por: Basson, Charlise, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_e82p0edie27juhj2d4nftcigci