The novel driver gene ASAP2 is a potential druggable target in pancreatic cancer

Targeting mutated oncogenes is an effective approach for treating cancer. The 4 main driver genes of pancreatic ductal adenocarcinoma (PDAC) are KRAS, TP53, CDKN2A, and SMAD4, collectively called the “big 4” of PDAC, however they remain challenging therapeutic targets. In this study, ArfGAP with SH3...

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Detalles Bibliográficos
Autores principales: Fujii, Atsushi, Masuda, Takaaki, Iwata, Michio, Tobo, Taro, Wakiyama, Hiroaki, Koike, Kensuke, Kosai, Keisuke, Nakano, Takafumi, Kuramitsu, Shotaro, Kitagawa, Akihiro, Sato, Kuniaki, Kouyama, Yuta, Shimizu, Dai, Matsumoto, Yoshihiro, Utsunomiya, Tohru, Ohtsuka, Takao, Yamanishi, Yoshihiro, Nakamura, Masafumi, Mimori, Koshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019229/
https://www.ncbi.nlm.nih.gov/pubmed/33605496
http://dx.doi.org/10.1111/cas.14858

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