PAR-4/Ca(2+)-calpain pathway activation stimulates platelet-derived microparticles in hyperglycemic type 2 diabetes

BACKGROUND: Patients with type 2 diabetes (T2DM) have a prothrombotic state that needs to be fully clarified; microparticles (MPs) have emerged as mediators and markers of this condition. Thus, we investigate, in vivo, in T2DM either with good (HbA1c ≤ 7.0%; GGC) or poor (HbA1c > 7.0%; PGC) glyce...

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Detalles Bibliográficos
Autores principales: Giannella, Alessandra, Ceolotto, Giulio, Radu, Claudia Maria, Cattelan, Arianna, Iori, Elisabetta, Benetti, Andrea, Fabris, Fabrizio, Simioni, Paolo, Avogaro, Angelo, Vigili de Kreutzenberg, Saula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019350/
https://www.ncbi.nlm.nih.gov/pubmed/33812377
http://dx.doi.org/10.1186/s12933-021-01267-w

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