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Patients with non-tuberculous mycobacteria in respiratory samples: a 5-year epidemiological study

BACKGROUND: This study describes the characteristics of patients with positive cultures of non-tuberculous mycobacteria (NTM) in respiratory samples and determines the risk factors that predispose for a reinfection with different NTM species. METHODS: Patients with NTM isolates in respiratory sample...

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Detalles Bibliográficos
Autores principales: López, Cristina Matesanz, Gallego, Cristina Loras, Calvo, Juana Cacho, Vasallo, Israel John Thuissard, Ramírez, María Teresa Río
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedad Española de Quimioterapia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019470/
https://www.ncbi.nlm.nih.gov/pubmed/33522212
http://dx.doi.org/10.37201/req/121.2020
Descripción
Sumario:BACKGROUND: This study describes the characteristics of patients with positive cultures of non-tuberculous mycobacteria (NTM) in respiratory samples and determines the risk factors that predispose for a reinfection with different NTM species. METHODS: Patients with NTM isolates in respiratory samples between 2013 and 2017 were studied. Additionally, risk factors and comorbidities of reinfected patients were analyzed. RESULTS: The study was focused on the 280 patients with NTM isolation (28 were reinfected with at least another species). Mycobacterium avium was the main isolated species. 68% were men. Median age was 73.2. Most remarkable risk factors were: tobacco, COPD and bronchiectasis. Bronchiectasis turned out to be a statistically significant risk factor for reinfection. Only 12 patients (12.4%) were treated.