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Targeting CXCR2 inhibits the progression of lung cancer and promotes therapeutic effect of cisplatin

BACKGROUND: Drug-resistance and severe side effects of chemotherapeutic agents result in unsatisfied survival of patients with lung cancer. CXCLs/CXCR2 axis plays an important role in progression of cancer including lung cancer. However, the specific anti-cancer mechanism of targeting CXCR2 remains...

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Detalles Bibliográficos
Autores principales: Cheng, Yuan, Mo, Fei, Li, Qingfang, Han, Xuejiao, Shi, Houhui, Chen, Siyuan, Wei, Yuquan, Wei, Xiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019513/
https://www.ncbi.nlm.nih.gov/pubmed/33814009
http://dx.doi.org/10.1186/s12943-021-01355-1