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RIPK3 Induces Cardiomyocyte Necroptosis via Inhibition of AMPK-Parkin-Mitophagy in Cardiac Remodelling after Myocardial Infarction

Receptor-interacting protein 3- (RIPK3-) modulated necroptosis plays a critical role in cardiac remodelling after myocardial infarction (MI). However, the precise regulatory mechanism is not fully elucidated yet. In the present study, we showed that RIPK3 expression was upregulated in myocardial tis...

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Detalles Bibliográficos
Autores principales: Zhu, Pingjun, Wan, Kun, Yin, Ming, Hu, Peng, Que, Yifan, Zhou, Xin, Zhang, Lei, Li, Tianzhi, Du, Yingzhen, Xu, Guogang, Fang, Xiangqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019651/
https://www.ncbi.nlm.nih.gov/pubmed/33854696
http://dx.doi.org/10.1155/2021/6635955