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RIPK3 Induces Cardiomyocyte Necroptosis via Inhibition of AMPK-Parkin-Mitophagy in Cardiac Remodelling after Myocardial Infarction
Receptor-interacting protein 3- (RIPK3-) modulated necroptosis plays a critical role in cardiac remodelling after myocardial infarction (MI). However, the precise regulatory mechanism is not fully elucidated yet. In the present study, we showed that RIPK3 expression was upregulated in myocardial tis...
Autores principales: | Zhu, Pingjun, Wan, Kun, Yin, Ming, Hu, Peng, Que, Yifan, Zhou, Xin, Zhang, Lei, Li, Tianzhi, Du, Yingzhen, Xu, Guogang, Fang, Xiangqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019651/ https://www.ncbi.nlm.nih.gov/pubmed/33854696 http://dx.doi.org/10.1155/2021/6635955 |
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