Nucleolin-Targeting AS1411 Aptamer-Modified Micelle for the Co-Delivery of Doxorubicin and miR-519c to Improve the Therapeutic Efficacy in Hepatocellular Carcinoma Treatment

BACKGROUND: Multidrug resistance (MDR) has emerged to be a major hindrance in cancer therapy, which contributes to the reduced sensitivity of cancer cells toward chemotherapeutic drugs mainly owing to the over-expression of drug efflux transporters. The combination of gene therapy and chemotherapy h...

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Detalles Bibliográficos
Autores principales: Liang, Xiao, Wang, Yudi, Shi, Hui, Dong, Mengmeng, Han, Haobo, Li, Quanshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019667/
https://www.ncbi.nlm.nih.gov/pubmed/33833512
http://dx.doi.org/10.2147/IJN.S304526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019667/
https://www.ncbi.nlm.nih.gov/pubmed/33833512
http://dx.doi.org/10.2147/IJN.S304526

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