Cargando…

Indoleamine 2,3-Dioxygenase 1 Inhibitor-Loaded Nanosheets Enhance CAR-T Cell Function in Esophageal Squamous Cell Carcinoma

In chimeric antigen receptor (CAR)-T cell therapy, the role and mechanism of indoleamine 2, 3 dioxygenase 1 (IDO1) in enhancing antitumor immunity require further study. IDO1 is one of the most important immunosuppressive proteins in esophageal squamous cell carcinoma (ESCC). However, the IDO1 inhib...

Descripción completa

Detalles Bibliográficos
Autores principales: Shao, Jingwen, Hou, Lin, Liu, Jinyan, Liu, Yulin, Ning, Jie, Zhao, Qitai, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019778/
https://www.ncbi.nlm.nih.gov/pubmed/33828565
http://dx.doi.org/10.3389/fimmu.2021.661357