Treatment With Endothelin-A Receptor Antagonist BQ123 Attenuates Acute Inflammation in Mice Through T-Cell-Dependent Polymorphonuclear Myeloid-Derived Suppressor Cell Activation

The endothelin-A receptor antagonist BQ123 is an effective treatment agent for hypertension and obese cardiomyopathy. However, the role of BQ123 in controlling acute inflammatory diseases and its underlying mechanisms are not well understood. Here, we showed that BQ123 activated polymorphonuclear my...

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Detalles Bibliográficos
Autores principales: Chen, Ziyang, Zhang, Xiaogang, Lv, Shuaijun, Xing, Zhe, Shi, Mengyu, Li, Xinyao, Chen, Meiqi, Zuo, Shaowen, Tao, Yingxu, Xiao, Gang, Liu, Jingping, He, Yumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019801/
https://www.ncbi.nlm.nih.gov/pubmed/33828553
http://dx.doi.org/10.3389/fimmu.2021.641874

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