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Transcriptomic Analysis of Mouse Brain After Traumatic Brain Injury Reveals That the Angiotensin Receptor Blocker Candesartan Acts Through Novel Pathways

Traumatic brain injury (TBI) results in complex pathological reactions, where the initial lesion is followed by secondary inflammation and edema. Our laboratory and others have reported that angiotensin receptor blockers (ARBs) have efficacy in improving recovery from traumatic brain injury in mice....

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Detalles Bibliográficos
Autores principales: Attilio, Peter J., Snapper, Dustin M., Rusnak, Milan, Isaac, Akira, Soltis, Anthony R., Wilkerson, Matthew D., Dalgard, Clifton L., Symes, Aviva J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019829/
https://www.ncbi.nlm.nih.gov/pubmed/33828448
http://dx.doi.org/10.3389/fnins.2021.636259