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Reduced Animal Models Fitting Only Equations for Phenotyped Animals

Reduced models are equivalent models to the full model that enable reduction in the computational demand for solving the problem, here, mixed model equations for estimating breeding values of selection candidates. Since phenotyped animals provide data to the model, the aim of this study was to reduc...

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Detalles Bibliográficos
Autores principales: Nilforooshan, Mohammad Ali, Garrick, Dorian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019830/
https://www.ncbi.nlm.nih.gov/pubmed/33828583
http://dx.doi.org/10.3389/fgene.2021.637626
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author Nilforooshan, Mohammad Ali
Garrick, Dorian
author_facet Nilforooshan, Mohammad Ali
Garrick, Dorian
author_sort Nilforooshan, Mohammad Ali
collection PubMed
description Reduced models are equivalent models to the full model that enable reduction in the computational demand for solving the problem, here, mixed model equations for estimating breeding values of selection candidates. Since phenotyped animals provide data to the model, the aim of this study was to reduce animal models to those equations corresponding to phenotyped animals. Non-phenotyped ancestral animals have normally been included in analyses as they facilitate formation of the inverse numerator relationship matrix. However, a reduced model can exclude those animals and obtain identical solutions for the breeding values of the animals of interest. Solutions corresponding to non-phenotyped animals can be back-solved from the solutions of phenotyped animals and specific blocks of the inverted relationship matrix. This idea was extended to other forms of animal model and the results from each reduced model (and back-solving) were identical to the results from the corresponding full model. Previous studies have been mainly focused on reduced animal models that absorb equations corresponding to non-parents and solve equations only for parents of phenotyped animals. These two types of reduced animal model can be combined to formulate only equations corresponding to phenotyped parents of phenotyped progeny.
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spelling pubmed-80198302021-04-06 Reduced Animal Models Fitting Only Equations for Phenotyped Animals Nilforooshan, Mohammad Ali Garrick, Dorian Front Genet Genetics Reduced models are equivalent models to the full model that enable reduction in the computational demand for solving the problem, here, mixed model equations for estimating breeding values of selection candidates. Since phenotyped animals provide data to the model, the aim of this study was to reduce animal models to those equations corresponding to phenotyped animals. Non-phenotyped ancestral animals have normally been included in analyses as they facilitate formation of the inverse numerator relationship matrix. However, a reduced model can exclude those animals and obtain identical solutions for the breeding values of the animals of interest. Solutions corresponding to non-phenotyped animals can be back-solved from the solutions of phenotyped animals and specific blocks of the inverted relationship matrix. This idea was extended to other forms of animal model and the results from each reduced model (and back-solving) were identical to the results from the corresponding full model. Previous studies have been mainly focused on reduced animal models that absorb equations corresponding to non-parents and solve equations only for parents of phenotyped animals. These two types of reduced animal model can be combined to formulate only equations corresponding to phenotyped parents of phenotyped progeny. Frontiers Media S.A. 2021-03-22 /pmc/articles/PMC8019830/ /pubmed/33828583 http://dx.doi.org/10.3389/fgene.2021.637626 Text en Copyright © 2021 Nilforooshan and Garrick. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Nilforooshan, Mohammad Ali
Garrick, Dorian
Reduced Animal Models Fitting Only Equations for Phenotyped Animals
title Reduced Animal Models Fitting Only Equations for Phenotyped Animals
title_full Reduced Animal Models Fitting Only Equations for Phenotyped Animals
title_fullStr Reduced Animal Models Fitting Only Equations for Phenotyped Animals
title_full_unstemmed Reduced Animal Models Fitting Only Equations for Phenotyped Animals
title_short Reduced Animal Models Fitting Only Equations for Phenotyped Animals
title_sort reduced animal models fitting only equations for phenotyped animals
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019830/
https://www.ncbi.nlm.nih.gov/pubmed/33828583
http://dx.doi.org/10.3389/fgene.2021.637626
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