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Reduced Animal Models Fitting Only Equations for Phenotyped Animals
Reduced models are equivalent models to the full model that enable reduction in the computational demand for solving the problem, here, mixed model equations for estimating breeding values of selection candidates. Since phenotyped animals provide data to the model, the aim of this study was to reduc...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019830/ https://www.ncbi.nlm.nih.gov/pubmed/33828583 http://dx.doi.org/10.3389/fgene.2021.637626 |
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author | Nilforooshan, Mohammad Ali Garrick, Dorian |
author_facet | Nilforooshan, Mohammad Ali Garrick, Dorian |
author_sort | Nilforooshan, Mohammad Ali |
collection | PubMed |
description | Reduced models are equivalent models to the full model that enable reduction in the computational demand for solving the problem, here, mixed model equations for estimating breeding values of selection candidates. Since phenotyped animals provide data to the model, the aim of this study was to reduce animal models to those equations corresponding to phenotyped animals. Non-phenotyped ancestral animals have normally been included in analyses as they facilitate formation of the inverse numerator relationship matrix. However, a reduced model can exclude those animals and obtain identical solutions for the breeding values of the animals of interest. Solutions corresponding to non-phenotyped animals can be back-solved from the solutions of phenotyped animals and specific blocks of the inverted relationship matrix. This idea was extended to other forms of animal model and the results from each reduced model (and back-solving) were identical to the results from the corresponding full model. Previous studies have been mainly focused on reduced animal models that absorb equations corresponding to non-parents and solve equations only for parents of phenotyped animals. These two types of reduced animal model can be combined to formulate only equations corresponding to phenotyped parents of phenotyped progeny. |
format | Online Article Text |
id | pubmed-8019830 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-80198302021-04-06 Reduced Animal Models Fitting Only Equations for Phenotyped Animals Nilforooshan, Mohammad Ali Garrick, Dorian Front Genet Genetics Reduced models are equivalent models to the full model that enable reduction in the computational demand for solving the problem, here, mixed model equations for estimating breeding values of selection candidates. Since phenotyped animals provide data to the model, the aim of this study was to reduce animal models to those equations corresponding to phenotyped animals. Non-phenotyped ancestral animals have normally been included in analyses as they facilitate formation of the inverse numerator relationship matrix. However, a reduced model can exclude those animals and obtain identical solutions for the breeding values of the animals of interest. Solutions corresponding to non-phenotyped animals can be back-solved from the solutions of phenotyped animals and specific blocks of the inverted relationship matrix. This idea was extended to other forms of animal model and the results from each reduced model (and back-solving) were identical to the results from the corresponding full model. Previous studies have been mainly focused on reduced animal models that absorb equations corresponding to non-parents and solve equations only for parents of phenotyped animals. These two types of reduced animal model can be combined to formulate only equations corresponding to phenotyped parents of phenotyped progeny. Frontiers Media S.A. 2021-03-22 /pmc/articles/PMC8019830/ /pubmed/33828583 http://dx.doi.org/10.3389/fgene.2021.637626 Text en Copyright © 2021 Nilforooshan and Garrick. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Genetics Nilforooshan, Mohammad Ali Garrick, Dorian Reduced Animal Models Fitting Only Equations for Phenotyped Animals |
title | Reduced Animal Models Fitting Only Equations for Phenotyped Animals |
title_full | Reduced Animal Models Fitting Only Equations for Phenotyped Animals |
title_fullStr | Reduced Animal Models Fitting Only Equations for Phenotyped Animals |
title_full_unstemmed | Reduced Animal Models Fitting Only Equations for Phenotyped Animals |
title_short | Reduced Animal Models Fitting Only Equations for Phenotyped Animals |
title_sort | reduced animal models fitting only equations for phenotyped animals |
topic | Genetics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019830/ https://www.ncbi.nlm.nih.gov/pubmed/33828583 http://dx.doi.org/10.3389/fgene.2021.637626 |
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