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Effects of Methylene Tetrahydro Folate Reductase Gene Polymorphisms on Methotrexate Toxicity in Egyptian Pediatric Acute Lymphocytic Leukaemia Patients

This study was designed to evaluate the effect of Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms on MTX toxicity in pediatric Egyptian ALL patients. Ninety-Four of Pediatric ALL patients aged 3–13 years (7.6 ± 3.6) on oral maintenance dose of 50 mg/m(2) weekly of MTX. MTHFR c.677C>...

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Detalles Bibliográficos
Autores principales:	Mostafa-Hedeab, Gomaa, Elborai, Yasser, Ebid, Gamal Thabet Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019867/ https://www.ncbi.nlm.nih.gov/pubmed/33841551 http://dx.doi.org/10.22037/ijpr.2020.1101296

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