Intracisternal administration of tanshinone IIA-loaded nanoparticles leads to reduced tissue injury and functional deficits in a porcine model of ischemic stroke

BACKGROUND: The absolute number of new stroke patients is annually increasing and there still remains only a few Food and Drug Administration (FDA) approved treatments with significant limitations available to patients. Tanshinone IIA (Tan IIA) is a promising potential therapeutic for ischemic strok...

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Detalles Bibliográficos
Autores principales: Waters, Elizabeth S., Kaiser, Erin E., Yang, Xueyuan, Fagan, Madison M., Scheulin, Kelly M., Jeon, Julie H., Shin, Soo K., Kinder, Holly A., Kumar, Anil, Platt, Simon R., Duberstein, Kylee J., Park, Hea Jin, Xie, Jin, West, Franklin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019951/
https://www.ncbi.nlm.nih.gov/pubmed/33842909
http://dx.doi.org/10.1016/j.ibneur.2020.11.003

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