Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016

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Monoclonal antibodies and antibody cocktails are a promising therapeutic and prophylaxis for coronavirus disease 2019 (COVID-19). However, ongoing evolution of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) can render monoclonal antibodies ineffective. Here, we completely map all of th...

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Detalles Bibliográficos
Autores principales: Starr, Tyler N., Greaney, Allison J., Dingens, Adam S., Bloom, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020059/
https://www.ncbi.nlm.nih.gov/pubmed/33842902
http://dx.doi.org/10.1016/j.xcrm.2021.100255

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