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Ca(2+)-activated Cl(−) channel TMEM16A inhibition by cholesterol promotes angiogenesis in endothelial cells

INTRODUCTION: Ca(2+)-activated Cl(−) channel TMEM16A is expressed in endothelial cells, and contributes to many diseases such as hypertension, blood-brain barrier dysfunction, and pulmonary hypertension. It remains unclear whether TMEM16A regulates endothelial angiogenesis, which participates in man...

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Detalles Bibliográficos
Autores principales:	Ma, Ke, Liu, Sitong, Liang, Hongyue, Wang, Guan, Wang, Tianyu, Luo, Shuya, Gao, Kuan, Wang, Hui, Liu, Mei, Bai, Lichuan, Xiao, Qinghuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020148/ https://www.ncbi.nlm.nih.gov/pubmed/33842002 http://dx.doi.org/10.1016/j.jare.2020.09.003

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