Heregulin-β1 Activates NF-E2-related Factor 2 and Induces Manganese Superoxide Dismutase Expression in Human Breast Cancer Cells via Protein Kinase B and Extracellular Signal-regulated Protein Kinase Signaling Pathways

Heregulin-β1, a ligand of ErbB-2 and ErbB-3/4 receptors, has been reported to potentiate oncogenicity and metastatic potential of breast cancer cells. In the present work, treatment of human mammary cancer (MCF-7) cells with heregulin-β1 resulted in enhanced cell migration and expression of manganes...

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Detalles Bibliográficos
Autores principales: Park, Ji-Young, Saeidi, Soma, Kim, Eun-Hee, Kim, Do-Hee, Na, Hye-Kyung, Keum, Joo-Seob, Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020172/
https://www.ncbi.nlm.nih.gov/pubmed/33842406
http://dx.doi.org/10.15430/JCP.2021.26.1.54

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