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The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism

OBJECTIVE: This study aimed to compare the pulmonary embolism (PE) location and clot burden on computed tomography pulmonary angiography (CTPA), the degree of right ventricular dysfunction (RVD), D-dimer, and cardiac troponin I (cTnI) levels, and the presence of a lower extremity deep venous thrombo...

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Autores principales: Caliskan, Tayfun, Turkoglu, Ozlem, Canoglu, Kadir, Ayten, Omer, Saylan, Bengu, Okutan, Oguzhan, Kartaloglu, Zafer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Istanbul Medeniyet University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020190/
https://www.ncbi.nlm.nih.gov/pubmed/33828887
http://dx.doi.org/10.5222/MMJ.2021.43066
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author Caliskan, Tayfun
Turkoglu, Ozlem
Canoglu, Kadir
Ayten, Omer
Saylan, Bengu
Okutan, Oguzhan
Kartaloglu, Zafer
author_facet Caliskan, Tayfun
Turkoglu, Ozlem
Canoglu, Kadir
Ayten, Omer
Saylan, Bengu
Okutan, Oguzhan
Kartaloglu, Zafer
author_sort Caliskan, Tayfun
collection PubMed
description OBJECTIVE: This study aimed to compare the pulmonary embolism (PE) location and clot burden on computed tomography pulmonary angiography (CTPA), the degree of right ventricular dysfunction (RVD), D-dimer, and cardiac troponin I (cTnI) levels, and the presence of a lower extremity deep venous thrombosis (DVT) in patients with and without cancer diagnosed with a non high risk pulmonary embolism (PE). METHOD: We calculated Miller score for each patient for clot burden. The location of PE was also evaluated at CTPA. D-dimer and cardiac cTnI levels were measured. Patients had echocardiography for RVD and lower extremity color flow Doppler ultrasonography for DVT. RESULTS: The study included 71 patients with PE. The patients were divided into two groups according to the presence of cancer. There was no statistically significant difference for D-dimer levels (P=0.15), PE location (p=0.67), clot burden (P=0.34), RVD (P=0.28) and DVT (P=0.33) between groups (P=0.15). Cancer patients diagnosed as PE had statistically significantly higher levels of cTnI than those who were diagnosed as PE without cancer (P=0.03). CONCLUSION: There was no significant difference between patients diagnosed as PE with and without cancer in terms of D-dimer levels, clot burden and emboli location, RVD and DVT. cTnI levels were higher in non-high risk PE patients with cancer than these patients without cancer.
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spelling pubmed-80201902021-04-06 The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism Caliskan, Tayfun Turkoglu, Ozlem Canoglu, Kadir Ayten, Omer Saylan, Bengu Okutan, Oguzhan Kartaloglu, Zafer Medeni Med J Original Study OBJECTIVE: This study aimed to compare the pulmonary embolism (PE) location and clot burden on computed tomography pulmonary angiography (CTPA), the degree of right ventricular dysfunction (RVD), D-dimer, and cardiac troponin I (cTnI) levels, and the presence of a lower extremity deep venous thrombosis (DVT) in patients with and without cancer diagnosed with a non high risk pulmonary embolism (PE). METHOD: We calculated Miller score for each patient for clot burden. The location of PE was also evaluated at CTPA. D-dimer and cardiac cTnI levels were measured. Patients had echocardiography for RVD and lower extremity color flow Doppler ultrasonography for DVT. RESULTS: The study included 71 patients with PE. The patients were divided into two groups according to the presence of cancer. There was no statistically significant difference for D-dimer levels (P=0.15), PE location (p=0.67), clot burden (P=0.34), RVD (P=0.28) and DVT (P=0.33) between groups (P=0.15). Cancer patients diagnosed as PE had statistically significantly higher levels of cTnI than those who were diagnosed as PE without cancer (P=0.03). CONCLUSION: There was no significant difference between patients diagnosed as PE with and without cancer in terms of D-dimer levels, clot burden and emboli location, RVD and DVT. cTnI levels were higher in non-high risk PE patients with cancer than these patients without cancer. Istanbul Medeniyet University 2021 2021-03-26 /pmc/articles/PMC8020190/ /pubmed/33828887 http://dx.doi.org/10.5222/MMJ.2021.43066 Text en © Copyright Istanbul Medeniyet University Faculty of Medicine. http://creativecommons.org/licenses/by-nc/4.0/ This journal is published by Logos Medical Publishing. Licenced by Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
spellingShingle Original Study
Caliskan, Tayfun
Turkoglu, Ozlem
Canoglu, Kadir
Ayten, Omer
Saylan, Bengu
Okutan, Oguzhan
Kartaloglu, Zafer
The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism
title The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism
title_full The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism
title_fullStr The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism
title_full_unstemmed The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism
title_short The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism
title_sort comparison between non-high risk patients with and without cancer diagnosed with pulmonary embolism
topic Original Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020190/
https://www.ncbi.nlm.nih.gov/pubmed/33828887
http://dx.doi.org/10.5222/MMJ.2021.43066
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