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The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism
OBJECTIVE: This study aimed to compare the pulmonary embolism (PE) location and clot burden on computed tomography pulmonary angiography (CTPA), the degree of right ventricular dysfunction (RVD), D-dimer, and cardiac troponin I (cTnI) levels, and the presence of a lower extremity deep venous thrombo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Istanbul Medeniyet University
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020190/ https://www.ncbi.nlm.nih.gov/pubmed/33828887 http://dx.doi.org/10.5222/MMJ.2021.43066 |
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author | Caliskan, Tayfun Turkoglu, Ozlem Canoglu, Kadir Ayten, Omer Saylan, Bengu Okutan, Oguzhan Kartaloglu, Zafer |
author_facet | Caliskan, Tayfun Turkoglu, Ozlem Canoglu, Kadir Ayten, Omer Saylan, Bengu Okutan, Oguzhan Kartaloglu, Zafer |
author_sort | Caliskan, Tayfun |
collection | PubMed |
description | OBJECTIVE: This study aimed to compare the pulmonary embolism (PE) location and clot burden on computed tomography pulmonary angiography (CTPA), the degree of right ventricular dysfunction (RVD), D-dimer, and cardiac troponin I (cTnI) levels, and the presence of a lower extremity deep venous thrombosis (DVT) in patients with and without cancer diagnosed with a non high risk pulmonary embolism (PE). METHOD: We calculated Miller score for each patient for clot burden. The location of PE was also evaluated at CTPA. D-dimer and cardiac cTnI levels were measured. Patients had echocardiography for RVD and lower extremity color flow Doppler ultrasonography for DVT. RESULTS: The study included 71 patients with PE. The patients were divided into two groups according to the presence of cancer. There was no statistically significant difference for D-dimer levels (P=0.15), PE location (p=0.67), clot burden (P=0.34), RVD (P=0.28) and DVT (P=0.33) between groups (P=0.15). Cancer patients diagnosed as PE had statistically significantly higher levels of cTnI than those who were diagnosed as PE without cancer (P=0.03). CONCLUSION: There was no significant difference between patients diagnosed as PE with and without cancer in terms of D-dimer levels, clot burden and emboli location, RVD and DVT. cTnI levels were higher in non-high risk PE patients with cancer than these patients without cancer. |
format | Online Article Text |
id | pubmed-8020190 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Istanbul Medeniyet University |
record_format | MEDLINE/PubMed |
spelling | pubmed-80201902021-04-06 The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism Caliskan, Tayfun Turkoglu, Ozlem Canoglu, Kadir Ayten, Omer Saylan, Bengu Okutan, Oguzhan Kartaloglu, Zafer Medeni Med J Original Study OBJECTIVE: This study aimed to compare the pulmonary embolism (PE) location and clot burden on computed tomography pulmonary angiography (CTPA), the degree of right ventricular dysfunction (RVD), D-dimer, and cardiac troponin I (cTnI) levels, and the presence of a lower extremity deep venous thrombosis (DVT) in patients with and without cancer diagnosed with a non high risk pulmonary embolism (PE). METHOD: We calculated Miller score for each patient for clot burden. The location of PE was also evaluated at CTPA. D-dimer and cardiac cTnI levels were measured. Patients had echocardiography for RVD and lower extremity color flow Doppler ultrasonography for DVT. RESULTS: The study included 71 patients with PE. The patients were divided into two groups according to the presence of cancer. There was no statistically significant difference for D-dimer levels (P=0.15), PE location (p=0.67), clot burden (P=0.34), RVD (P=0.28) and DVT (P=0.33) between groups (P=0.15). Cancer patients diagnosed as PE had statistically significantly higher levels of cTnI than those who were diagnosed as PE without cancer (P=0.03). CONCLUSION: There was no significant difference between patients diagnosed as PE with and without cancer in terms of D-dimer levels, clot burden and emboli location, RVD and DVT. cTnI levels were higher in non-high risk PE patients with cancer than these patients without cancer. Istanbul Medeniyet University 2021 2021-03-26 /pmc/articles/PMC8020190/ /pubmed/33828887 http://dx.doi.org/10.5222/MMJ.2021.43066 Text en © Copyright Istanbul Medeniyet University Faculty of Medicine. http://creativecommons.org/licenses/by-nc/4.0/ This journal is published by Logos Medical Publishing. Licenced by Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) |
spellingShingle | Original Study Caliskan, Tayfun Turkoglu, Ozlem Canoglu, Kadir Ayten, Omer Saylan, Bengu Okutan, Oguzhan Kartaloglu, Zafer The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism |
title | The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism |
title_full | The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism |
title_fullStr | The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism |
title_full_unstemmed | The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism |
title_short | The Comparison Between Non-High Risk Patients with and Without Cancer Diagnosed with Pulmonary Embolism |
title_sort | comparison between non-high risk patients with and without cancer diagnosed with pulmonary embolism |
topic | Original Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020190/ https://www.ncbi.nlm.nih.gov/pubmed/33828887 http://dx.doi.org/10.5222/MMJ.2021.43066 |
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